Abstract
Sinusitis
Hygeia.J.D.Med, 2(1), 2010, 1-15
SINUSITIS
SiyadA. R
Departmentof Pharmacy Practice, Crescent Collegeof Pharmaceutical Sciences ,Kannur,Kerala, India, 670358
Article history: Received: 21 December 2009,accepted: 15 February 2010
Sinusitis isthe fifth common diagnosis for which an anti biotic is prescribed and about $ 2billion is spent annually on medications to treat nasal and sinus problems.Diagnosis and treating sinusitis is therefore being very important .Acute bacterial sinusitis usuallyoccurs following an upper respiratory infection that result in the obstruction of the osteomeatal complex , impaired mucociliary clearance and production of secretions (L.J.Fajan et al ,1989.)
Acute sinusitis is a common illness in primarycare .Studies have demonstrated the difficulty of making the differentialdiagnosis of acute purulent sinusitis based on clinical evaluations alone. This leads to a significant overuse of antibiotics, whichin turn may contribute to increase bacterial resistance. (Morten Lindback. et al.,2002). Sinus diseaseis inherently associated with viralupper respiratory tract infections and occurs in 90% of individuals with common cold. Although thediagnosis of acute bacterial sinusitis is usually based on physical findings, no one sign or symptom iseither sensitive or specific for sinusitis. The predictive power can be significantlyimproved when all signs and symptoms iseither sensitive or specific for sinusitis. (Martin Desrosiers. et al.,2002)There is solid evidence that a positive association between nasal allergyand acute or chronic sinusitis in bothadult and children. (Shin- Wen Huang. et al., 2006 . Acute sinusitis frequentlyfollows upper respiratory tractinfections. Sinusitis or an inflammation of one or more of the para nasalsinuses, affects approximately 16% of USadults, resulting in nearly $ 5.8 billion in annual healthcare costs. (LauriaBarclay et al)