Abstract
Biological prospective of 4-thiazolidinone: a review.
Hygeia.J.D.Med. 2017; 9 (1):80-97
DOI: 10.15254/H.J.D.Med.9.2017.166
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Rakesh kumar1* and Shailendra Patil2.
1.Vaish Institute of Pharmaceutical Education and Research, Rohtak-124001, Haryana, India
2. SVN Institute of Pharmaceutical Sciences, Swami Vivekanand University, Sagar- 470003
ABSTRACT
Plan: Biological prospective of 4-thiazolidinone
Prologue: 4-Thiazolidinones are derivatives of thiazolidine with a carbonyl group in the 4th position. Substitution on the 2nd, 3rd and 5th positions may be varied, but the greatest difference in the structure and properties is exerted by the group attached to the carbon atom on the 2nd position.
Methodology: 4-Thiazolidinones exhibited a broad spectrum of biological activities viz: anticancer, antimicrobial, antimycobacterial, antiviral, anti-HIV, analgesic, anti-inflammatory, antioxidant, anticonvulsant, antidiabetic, antimalarial, anti-hypertension, antiarrhythmic, antiprotozoal, hypolipidemic, etc.
Outcome: This study is an attempt to address the various biological potential of 4-thiazolidinone. Information provided in this manuscript may be useful for further investigations on this scaffold.
Keywords: 4-Thiazolidinone, chemistry of 4-thiazolidinone, Biological Potential
Correspondence
Rakesh kumar M.Pharm
Vaish Institute of Pharmaceutical Education and Research, Rohtak-124001, Haryana, INDIA
rakesh.gupta199@gmail.com
Mob No: +919812344450
Article History: Received: 22 September 2016, Revised: 2 February 2017Accepted: 20 June 2017, Available online: 15 July 2017
Article citation
Rakesh kumar and Shailendra Patil. Biological prospective of 4-thiazolidinone: a review. Hygeia.J.D.Med 2017; 9(1):80-97. Available from http://www.hygeiajournal.com , DOI: 10.15254/H.J.D.Med.9.2017.166
4-Thiazolidinone