Hygeia journal for drugs and medicines


A Review on Novel oral Anticoagulants

Hygeia.J.D.Med 2015; 7(2):51-56. 

GreetyT.J, K. Krishna Kumar, K. Jayapraksah, L. Panayappan*

Department of Pharmacy Practice, St James College of Pharmaceutical Sciences, Chalakudy, Kerala
St James Hospital Trust Pharmaceutical Research Centre, Chalakudy, Kerala

Corresponding author email: stjamesdruginfo@gmail.com 

Plan: This article reveals the significance of novel oral anticoagulants in place of conventional vitamin K antagonists. Vitamin K antagonists were commonly used since 1941 but it has lot of inconveniences. 

Preface: Anticoagulants are drugs used to reduce the coagulability of blood. Mainly used for the prevention of disorders characterized by abnormal blood clots and embolism.Warfarin, a vitamin K antagonist was the only choice for chronic oral anticoagulation for more than half a century. It requires periodic monitoring of INR, its efficacy and safety depends upon time in the therapeutic range.

Outcome: Recently novel oral anticoagulants (NOAC’s) have been introduced, offering similar effectiveness, safety and convenience of vitamin K antagonist not requiring lab monitoring. This review describes the currently approved NOAC’s.

Keywords: Novel oral anticoagulant (NOAC); atrial fibrillation (AF)

Article citation 

Greety T.J, K. Krishna Kumar, K.Jayapraksah, L. Panayappan. A review on novel oral anticoagulants. Hygeia.J.D.Med2015;7(2):51-56. Available from http://www.hygeiajournal.com / Article ID-Hygeia.J.D.Med/151/15.   DOI: 10.15254/H.J.D.Med.7.2015.151.


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