Abstract
Antiulcer activity of the Leaf ethanolic extract of Mimosa pudica in Rats
Hygeia.J.D.Med.4(1),April 2012-October 2012,34-40
Authors : Elango.V1, Carolin Oliver1 and Raghu, P.S.2*
Affiliations:
1. Dept of Siddha Medicine, Faculty of Sciences, Tamil university, Thanjavur-613 010, Tamilnadu, India
2. Mohammadia Institute of Pharmacy, Arambula, Khammam-507163, Andhra Pradesh, India.
Article history:
Received: 19 Jan. 2012
Revised: 25 Jan. 2012,
Accepted: 15 February 2012
Available online: 05 April 2012
Abstract:
Plan: The present study was designed to investigate the antiulcer potential of ethanolic extract of Mimosa pudica leaves.
Methodology: Antiulcer activity was evaluated by pylorus ligation, aspirin and ethanol induced ulcer models. The ethanolic extract of the leaves of Mimosa pudica was given by oral route at a dose of 100 mg/kg b.w.
Outcome: Ethanolic extract of Mimosa pudica, dose dependently reduce, the total acidity, ulcer index, and an increase in pH of gastric juice in pylorus ligated ulcer model. Extract of Mimosa pudica may be useful as a natural antioxidant in the treatment of ulcer.
Keywords: Antiulcer Activity, Mimosa pudica, leaf ethanolic extract
Article outline
1.Introduction
2.Materials and methods
3.conclusion
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