Hygeia journal for drugs and medicines



Hygeia J. D. MedVol.3 (1) April 2011- September 2011, 20-28.

Type of Article: Research review

Kishore Kumar. P, Raju A. B.

St.Peters Institute ofPharmaceutical Sciences, Hanamkonda, Warangal, Andhra Pradesh,India-506001.

Article history: Received: 03 February2011, revised: 25February, 2011, accepted: 3 March, 2011, Availableonline: 14 April 2011

  Spermatogenesis is a complex process that involves stem-cell renewal, genome reorganization and genome repackaging, and that culminates in the production of motile gametes. Problemsat all stages of spermatogenesis contribute to human infertility. Male infertility, is characterizedby hypogonadism, decreased semen quality or ejaculatory dysfunction, accountsfor approximately 20% of infertility cases. The main cause for infertilityapoptosis. Apoptosis, a form of programmed cell death in contrastto necrosis, which represents "accidental cell death," plays animportant role in spermatogenesis.
excessive alcohol intake resultedin Leydig cell apoptosis, while cocaine resulted in mitochondrial apoptosis, excessive alcohol intake resultedin Leydig cell apoptosis, while cocaine resulted in mitochondrial apoptosis. Men with severe oligozoospermialess than 1 to 5 x 106 sperm/ml are considered as a maleinfertility by diagnosis. Studieson male infertility,potentially opening the door for treatment advances for improving spermatogenesis. Newer techniques like sperm retrieval and VE modifications are promising and becoming increasingly more  popular
for the estimation of damage ofcertain DNA is responsible for male infertility.

Keywords: Male Infertility, Diabetes, SpermDNA, Impotence.

Article outline

1. Infertility

2.Causes of Infertility

3.Diagnosis of Infertility in male

4. Prevention of male infertility

For downloading full text articles and issues in PDF, at free of cost , you have to  fillup the hygeia registration form.  At any time, you may request for the removal of your contact information from our website database.

For Correspondence:


© 2011 Hygeia journal for drugs and medicinesallrights reserved.  2229 3590, 0975 6221


  • watch Video
    Collagen Mimetic Peptides
  • watch Video
    Mechanisms and secrets of Alzheimer's disease...
  • watch Video
    Immunotherapy to fight cancer
  • watch Video
    Food Safety Emergency Prevention
  • watch Video
    Tiny worm-like robot could deliver medicine inside body
  • watch Video
    This smart pill could crawl through your body to deliver its medicine
  • watch Video
    Introduction To Nanorobotics: A conversation